ChemicalBook > CAS DataBase List > Afurolol
Afurolol
- Product Name
- Afurolol
- CAS No.
- 65776-67-2
- Chemical Name
- Afurolol
- Synonyms
- Afurolol;Afurololum;7-[3-(tert-Butylamino)-2-hydroxypropoxy]isobenzofuran-1(3H)-one;1(3H)-Isobenzofuranone, 7-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-
- CBNumber
- CB41116269
- Molecular Formula
- C15H21NO4
- Formula Weight
- 279.33154
- MOL File
- 65776-67-2.mol
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0016567
- Product name
- AFUROLOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.94
- Updated
- 2021/12/16
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Afurolol Chemical Properties,Usage,Production
Originator
Afurolol ,ZYF Pharm Chemical
Manufacturing Process
A mixture of 18.0 g (0.12 mole) 7-hydroxyphthalide, 180.0 g of 1-chloro-2,3-
epoxypropane (2 moles) and 0.5 ml of piperidine is heated at 100°C for about
5 h and then the unreacted 1-chloro-2,3-epoxypropane is distilled off in
vacuum to yield 12.0 g (48%) of 7-(2,3-epoxypropoxy)phthalide, melting
point 88°-90°C, (crystallized successively from methanol and ethyl acetate).
The 7-(2,3-epoxypropoxy)phthalide is dissolved in methanol and t-butylamine
are added to the solution at about 20°C. The solution is allowed to stand overnight and, the mixture is evaporated in vacuum and the residue is dried
to give 7-(2-hydroxy-3-t-butylamino-propoxy)phthalide.
Therapeutic Function
Beta-adrenergic blocker
Afurolol Preparation Products And Raw materials
Raw materials
Preparation Products
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Afurolol Suppliers
65776-67-2, AfurololRelated Search:
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